(+)-Alfa-barbatenska sintaza
(+)-Alfa-barbatenska sintaza (EC 4.2.3.69, AtBS) je enzim sa sistematskim imenom (2E,6E)-farnezil-difosfat difosfat-lijaza (formira (+)-alfa-barbaten).[1][2] Ovaj enzim katalizira sljedeću kemijsku reakciju
(+)-Alfa-barbatenska sintaza | |||||||||
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Identifikatori | |||||||||
EC broj | 4.2.3.69 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz unos | ||||||||
BRENDA | BRENDA unos | ||||||||
ExPASy | NiceZyme unos | ||||||||
KEGG | KEGG unos | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profil | ||||||||
PDB struktura | RCSB PDB PDBe PDBsum | ||||||||
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- (2E,6E)-farnezil difosfat (+)-alfa-barbaten + difosfat
Rekombinirajući enzim iz biljke Arabidopsis thaliana formira 27.3% alfa-barbatena, 17.8% tujopsena i 9.9% beta-hamigrena.
Izvori
uredi- ↑ Wu, S., Schoenbeck, M.A., Greenhagen, B.T., Takahashi, S., Lee, S., Coates, R.M. and Chappell, J. 2005. Surrogate splicing for functional analysis of sesquiterpene synthase genes. Plant Physiol. 138: 1322–1333. PMID 15965019CS1 održavanje: više imena: authors list (link)
- ↑ Tholl, D., Chen, F., Petri, J., Gershenzon, J. and Pichersky, E. 2005. Two sesquiterpene synthases are responsible for the complex mixture of sesquiterpenes emitted from Arabidopsis flowers. Plant J. 42: 757–771. PMID 15918888CS1 održavanje: više imena: authors list (link)
Literatura
uredi- Nicholas C. Price, Lewis Stevens. 1999. Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins Third izdanje. Oxford University Press. USA. ISBN 019850229X
- Eric J. Toone. 2006. Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution Volume 75 izdanje. Wiley-Interscience. ISBN 0471205036
- Branden C, Tooze J. Introduction to Protein Structure. Garland Publishing. New York, NY. ISBN 0815323050. Inačica izvorne stranice arhivirana 22. studenoga 2010. Pristupljeno 19. studenoga 2016.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems Book 44 izdanje. Wiley Classics Library. ISBN 0471303097
- Robert A. Copeland. 2013. Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists 2nd izdanje. Wiley-Interscience. ISBN 111848813X
- Gerhard Michal, Dietmar Schomburg. 2012. Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology 2nd izdanje. Wiley. ISBN 0470146842